Preventing academic difficulties in preterm children: A randomized controlled trial of an adaptive working memory training intervention – IMPRINT study

Institution: Murdoch Research Institute

Investigator(s): Professor Peter Anderson, Professor Lex Doyle, Dr. Gehan Roberts, Professor Susan Gathercole, Dr. Chiara Nosarti, Dr. Deanne Thompson, Dr. Marc Seal, Dr. Katherline Lee, Dr. Gillian Opie, Dr. Elizabeth Carse

Program: Cogmed RM

Background & Aim: About 10% of live births per year are preterm. Increases in the number of preterm children who survive can be attributed to advances in perinatal and neonatal medicine. In shifting focus from improving chances of survival, research is now focusing on improving the quality of life for individuals born preterm. Children born at very or extremely low birth weights exhibit compromised WM and are at increased risk for educational, social and intellectual problems. Thus, this study aims to assess the effectiveness of Cogmed to improve academic functioning at 24 months post-intervention in extremely preterm (EP)/extremely low birth weight (ELBW) children and to investigate training-induced neuroplasticity associated with Cogmed training 2 weeks following Cogmed.

Population & Sample Size: N = 126 children born at EP/ELBW, age 7 years

Design: Randomized, Placebo controlled, Double-blinded, Test-retest, 12-14 month follow-up