Feasibility study of computerized working memory training in Fragile X Syndrome

Institution: University of California, Davis

Investigator(s): Dr. Julie Schweitzer, Dr. Randi Hagerman, Dr. David Hessl, Dr. Andrea Schneider

Program: Cogmed RM

Background & Aim: Working memory (WM) is significantly impaired in person with Fragile X Syndrome (FXS). Research has demonstrated that individuals with FXS have aberrant fronto-striatal brain activation that underlies their working memory deficit. The aim of this pilot project is to determine the feasibility of using a computerized WM training program (Cogmed) to improve attention and memory functioning in children and young adults with FXS and to examine the effectiveness of the training on learning, attention, memory and behavior.

Population & Sample Size: N = 30 children & adults with Fragile X in adaptive Cogmed training group, ages 6 -25 years

Design: Feasibility, Test-retest