Neuroplastic brain changes in children and adults

Institution: McMaster University

Investigator(s): Geoffery Hall, Ph.D.

Program: Cogmed RM

Background & Aim: This research will examine the changes in brain structure and function that underlie computer-based neuro-plasticity training (Cogmed) in two successive studies. The first study will examine a group of young adults, and will make use of the Cogmed Working Memory Training Program. We hypothesize that training based improvements on memory performance will be associated with greater EEG phase synchrony in WM networks and increases in theta band power. The second study will examine children 7 to 10 years of age, and will make use of the Cogmed Working Memory Training Program designed for school aged children and Magnetic Resonance Imaging methods. In this study, we plan to use Diffusion Tensor Imaging to examine changes in white matter structure that are concurrent with the consolidation of functional neural networks (fMRI – Resting State) post-training.

Population & Sample Size: N = 30 typically functioning adults, age 18+ and N = 30 healthy children born pre-term, ages 7- 10 years

Design: Randomized, Passive-Controlled, Test-retest