The effect of cognitive training on alcohol consumption, cognition and craving in alcohol use disorders

Institution: Karolinska Institute

Investigator(s): Nitya Jayaram-Lindström, Ph.D., Lofti Khemiri, M.D.

Program: Cogmed QM

Background & Aim: Alcohol dependence (AD) is a chronic relapsing psychiatric disorder characterized by physiological dependence, loss of control over drinking, and abandonment of other important activities (Koob, 2003). The lifetime prevalence of AD in Sweden is 10 – 14% and alcohol consumption has increased throughout the 20th century. Consequences of AD include unemployment, compromised family relations, as well as increased morbidity and mortality (e.g., psychiatric illness, suicide, accidents, and liver disease). Despite the negative health effects of alcohol consumption, treatment options are still limited and there is thus a need to develop efficacious interventions to reduce alcohol consumption and prevent craving and relapse. The purpose of this research is therefore to evaluate the potential utility of Cogmed Working Memory Training in improving cognitive impairments and alcohol use outcomes in persons with alcohol disorders.

Population & Sample Size: N = 50 adults with alcohol use disorder, ages 18 – 60 years

Design: Randomized, Placebo controlled, Double-blinded, Test-retest