Computerized working memory training evaluated with clinical assessments and quantitative EEG in very-low-birth-weight (VLBW) children at preschool age

Institution: Norwegian University of Science and Technology

Investigator(s): Dr. Jon Skranes, Dr. Ann-Mari Brubakk, Dr. Gro Løhaugen, Dr. Kristine Hermansen Grunewaldt

Program: Cogmed RM

Background & Aim: Children born preterm are at increased risk of neurological disabilities due to perinatal brain damage. Major impairments including cerebral palsy, mental retardation and impaired vision and hearing are most common in children born extremely preterm (gestational age below 28 weeks). In addition to this, a large part of survivors after preterm birth will experience motor problems, cognitive dysfunctions, psychiatric and behavioural problems of varying severity. Preterm children also are vulnerable to reduced hippocampal volume and white matter injury, which are associated with a compromised WM system. The aim of this research is to compare quantitative EEG findings and cognitive and neuropsychological test results before and after training with Cogmed JM in a group of Very Low Birth Weight (VLBW; birth weight ≤ 1500 grams) children of preschool age.

Population & Sample Size: N = 30 children born at VLBW, ages 5 -6 years

Design: Randomized, Waitlist controlled, Test-retest, 6 month follow-up